MCQ Chapter 6 Molecular Basis of Inheritance Class 12 Biology

Please refer to Molecular Basis of Inheritance MCQ Questions Class 12 Biology below. These MCQ questions for Class 12 Biology with answers have been designed as per the latest NCERT, CBSE books, and syllabus issued for the current academic year. These objective questions for Molecular Basis of Inheritance will help you to prepare for the exams and get more marks.

Molecular Basis of Inheritance MCQ Questions Class 12 Biology

Please see solved MCQ Questions for Principles of Inheritance and Variation in Class 12 Biology. All questions and answers have been prepared by expert faculty of standard 12 based on the latest examination guidelines.

MCQ Questions Class 12 Biology Molecular Basis of Inheritance

Question- In split genes, the coding sequences are called
(a) introns
(b) exons
(c) cistrons
(d) operons  

Question- Which of the following RNA polymerase catalyses the formation of transfer RNA in eukaryotes?
(a) RNA polymerase I
(b) RNA polymerase II
(c) RNA polymerase I and II
(d) RNA polymerase III

Question- Hydrogen bonds occur between which of the following constituents of DNA?
(a) sugar and base
(b) phosphate and base
(c) complementary bases
(d) phosphate and sugar

Question- How many pairs nucleotides are present in one turn of DNA helix?
(a) 4
(b) 8
(c) 9
(d) 10  

Question- Okazaki fragments are formed during
(a) transcription
(b) translation
(c) replication
(d) transduction   

Question- DNA duplication or multiplication is called
(a) transcription
(b) translation
(c) transaction
(d) replication

Question- Watson and Crick proposed the model of DNA structure in
(a) 1943
(b) 1953
(c) 1963
(d) 1965  

Question- Part of DNA which switch their positions are called
(a) cistrons
(b) transposons
(c) exons
(d) introns

Question- The terms cistron, recon and muton were proposed by
(a) Benzer
(b) Morgan
(c) Lederberg
(d) Johansen  

Question- DNA replication requires
(a) DNA polymerase only
(b) DNA ligase only
(c) RNA polymerase and translocase
(d) DNA polymerase and DNA ligase  

Question- Nonsense codon is responsible for
(a) elongation of polypeptide chain
(b) termination of protein synthesis
(c) putting a wrong amino acid
(d) hydrolysis of GTP 

Question- Which one is not applicable in respect of genetic code?
(a) Overlapping
(b) Redundancy
(c) Degeneracy
(d) Univers ty 

Question- Which of the following sugars is found in RNA?
(a) Hexose
(b) Fructose
(c) Ribose
(d) Glucose  

Question- One gene one enzyme hypothesis was proposed by
(a) Jacob and Monod
(b) Watson and Crick
(c) Garrod and Jenson
(d) Beadle and Tatum 

Question- Ligase is an enzyme required for
(a) proofreading
(b) joining DNA bits
(c) breaking of DNA
(d) renaturation of DNA 

Question- The chain-terminating codon is
(a) AUG
(b) CCC
(c) UAG
(d) GGG 

Question- In one strand of DNA the sequence of bases is AAATGGCCCTT, then the complementary sequence of bases on the other side of the strand would be
(a) ATATGGCCCCA
(b) TTTACCGGGAA
(c) TTTTGGCCAM
(d) TTTTGGCCCAA 

Question- In bacterial chromosome
(a) there is one origin of replication
(b) there are multiple sites of replication
(c) there is no repair of DNA
(d) replication is very slow   

Question- The tryptophan bperon is transcribed
(a) when there is plenty of tryptophan in the cell,
(b) when there is no tryptophan in the cell
(c) when lactose is present
(d) even without RNA polymerase 

Question- What is a codon?
(a) agroupofthreedeoxyribonucleotides
(b) a group of three ribonucleotides
(c) a unit of mutation
(d) a group of four ribonucleotides 

Question- Viriods differe from viruses in-
(a) Naked DNA molecules
(b) Naked DNA packaged in viral genera
(c) Naked RNA molecules
(d) Naked RNA with protein coat 

Question- Out of 64 codons how many of them code for amino acids?
(a) 4
(b) 20
(c) 61
(d) 32 

Question- Experimental evidence supporting concept of triplet genetic code was first provided by
(a) Watson
(b) Crick
(c) Michaelis and Menten
(d) Beadle and Tatum   

Question- In 1928 Frederick Griffith showed that the hereditary material can pass from one type of bacteria into another through a process called
(a) transduction
(b) invasion
(c) recombination
(d) transformation  

Question- The external supply of tryptophan in Escherichia coli brings about
(a) switching on of lac operon
(b) switching off of lac operon
(c) switching on of tryptophan operon
(d) switching off of tryptophan operon 

Question- The transforming substance of pneumococcus in Griffith’s experiment was
(a) protein
(b) RNA
(c) DNA
(d) polysaccharide   

Question- In 1868 DNA was discovered by the Swedish biochemist
(a) Feulgen
(b) Luria
(c) Mirsky
(d) Friedrich Miescher  

Question- The end product of a metabolic pathway may bind a repressor to make the latter active enough to bind to the operator, in which case the end-product is called
(a) inducer
(b) accelerator
(c) corepressor
(d) aporepressor  

Question- Enzyme required for transcription is
(a) DNA polymerase
(b) RNA polymerase
(c) RNA-ase
(d) endonuciease   

Question- Escherichia co//with completely radioactive DMA was allowed to replicate in nonradioactive medium for two generations. Percentage of bacteria with radioactive DMA is
(a) 12.5%
(b) 25%
(c) 50%
(d) 100%  

Question- Synthesis of DNA from RNA template occurs in
(a) reovirus
(b) rous sajcoma virus
(c) T2
(d) TMV   

Question- Which one is correct?
(a) DNA replication occurs before mitosis, meiosis and amitosis.
(b) The polarity of DNA template on which leading strand forms is 3′ —» 5′.
(c) The products of gene may be rRNA, tRNA and mRNA.
(d) All of the above

Question- What is the distance between two base pairs in the double helix model of DNA?
(a) 0.34nm
(b) 34nm
(c) 5A°
(d) 10A°   

Question- Transcription refers to the
(a) transfer of genetic code or sequences of DNA into RNA
(b) formation of DMA from RNA
(c) formation of protein
(d) polymerisation of RNA in cell-free system

Question- RNA that picks up specific amino acid from amino acid pool of cytoplasm to carry it to ribosome during protein synthesis is
(a) mRNA
(b) tRNA
(c) rRNA
(d) gRNA  

Question- The functional unit of gene that specifies synthesis of one polypeptide is
(a) muton
(b) recon
(c) cistron
(d) codon  

Question- Information transfer from RNA to DNA is called
(a) replication
(b) reverse transcription
(c) translation
(d) transcription  

Question- In operon model, RNA polymerase binds to
(a) structural gene
(b) operator gene
(c) promoter gene
(d) regulator 

Question- Which one of the following synthesizes a represser protein?
(a) Regulator gene
(b) Promoter gene
(c) Structural gene
(d) Operator gene 

Question- Isotopes used in proving semiconservative replication of DNA were
(a) 14N14C
(b) 14N15N
(c) 14N 31P
(d) 14C31P   

Question- Protein coat of a virus in called-
(a) virus
(b) copsid
(c) copsomeres
(d) Cell wall    

Question- Generally only one strand of DNA is transcribed. This strand is called
(a) A strand
(b) B strand
(c) sense strand
(d) template strand  

Question- Genetic code translates the languagespf
(a) RNA into that of protein
(b) RNA into that of DNA
(c) amino acids into that of RNA
(d) protein into that of DNA   

Question- DNA duplex shows
(a) left handed and parallel coiling
(b) left handed and antiparailel coiling
(c) right handed and parallel coiling
(d) right handed and antiparailel coiling  

Question- A large cluster of ribosomes is called
(a) megasome
(b) microsome
(c) oligosome
(d) polyribosome

Question- The site of tRNA that binds to mRNA is
(a) codon
(b) anticodon
(c) 5’ end
(d) 3’ end  

Question- Triplet codon refers to sequence of three bases oh
(a) tRNA
(b) rRNA
(c) mRNA
(d) alil of these c

Question- Viruses parasiting in bacteria are-
(a) Bacteriophages
(b) Phytophages
(c) Cyanophages
(d) Bacterio-viruses   

Question- The difference in A, B and Z forms of DNA lie in
(a) base sequences’
(b) parallelism of chains
(c) hydrogen bonding
(d) internucleotide distances  

Question- Reverse transcription was discovered by .
(a) Beadle and Tatum
(b) Watson and Crick
(c) Khorana
(d) Temin and Baltimore