Worksheets Class 12 Biology Molecular Basis of Inheritance

Students should refer to Worksheets Class 12 Biology Molecular Basis of Inheritance Chapter 6 provided below with important questions and answers. These important questions with solutions for Chapter 6 Molecular Basis of Inheritance have been prepared by expert teachers for Class 12 Biology based on the expected pattern of questions in the class 12 exams. We have provided Worksheets for Class 12 Biology for all chapters on our website. You should carefully learn all the important examinations questions provided below as they will help you to get better marks in your class tests and exams.

Molecular Basis of Inheritance Worksheets Class 12 Biology

Question. In nucleoside which of the following bond exists between sugar and nitrogenaous base
(a) Phosphodiester bond
(b) Hydrogen bond
(c) Phosphoester bond
(d) N-glycosidic bond

Question. By which of the following bond phosphoric acid remain linked with 5′ carbon of sugar in one nucleotide
(a) Phosphoester bond
(b) Phosphodiester bond
(c) N-Glycosidic bodn
(d) Hydrogen bond

Question. If E.Coli is allow to grow for 80 minutes in 15NH4Cl medium then what would be the proportion of hybrid and heavy density DNA molecules
(a) 1 : 7
(b) 7 : 1
(c) 14 : 2
(d) 1 : 4

Question. Which of the following cell cycle event is responsible for aneuploidy based chromosomal disorders
(a) Failure of G1 phase
(b) Failure ofDNA replication in s-phase
(c) Failure of segregation/Disjunction
(d) Failure of movement of chromosomes

Question. How much duration of time required for replication of 4.6 x 106pb in E.coli
(a) 83 minutes
(b) 20 minutes
(c) 2 minutes
(d) 3 hrs

Question. What is the rate of polymerisation in E.coli
(a) 20,000 bp per second
(b) 2000 nucleotides per second
(c) 2000 bp per minute
(d) 2000 bp per second

Question. During replication large amount of energy get exhausted. The source of this energy is
(a) Deoxy ribonucleotide triphosphophate
(b) Deoxyribonucleoside monoplosphate
(c) Deoxyribonucleoside triphosphate
(d) Both 1 and 2

Question. Regarding to direction of DNA replication select out the correct one
(a) 5′ → 3′ Template – continuous synthesis
(b) 3′ → 5′ Template – discontinuous synthesis
(c) 3′ → 5′ Template – continuous synthesis
(d) 5′ → 3′ Template – synthesis leadingstrand

38. Which of the following scheme of replication fork is true   D

Question. In transcription unit promoter and terminator are determined on the basis of
(a) Coding strand
(b) Template strand
(c) Noncoding strand
(d) Antisense strand

Question. In eukaryotes as well as prokaryotes those DNA sequences that appear in mature or processed RNA are known as
(a) Introts
(b) Exons
(c) Recons
(d) Mutons

Question. Regarding to role of RNA in protein synthesis find out the odd one
(a) m-RNA – provides the template
(b) t-RNA – brings aminoacids
(c) r-RNA – read genetic code
(d) sn-RNA splicing

Question. What is the basis of heredity
(a) Variations
(b) Inheritance
(c) Genetics
(d) Recombination

Question. Change in a single base pair of DNA can be termed as
(a) Chromosomal aberrations
(b) Point mutation
(c) Genomatric mutation
(d) Frame shift mutation

Question. Which of the following exclusive property of trancription found in RNA-polymerase
(a) Initiation
(b) Elongation
(c) Termination
(d) Processing

Question. Which of the folloiwng is not a criteria for determination of genetic material
(a) Ability of replication
(b) Chemically and structurally stable
(c) It should be non mutable
(d) Ability to expres itself in from of Mendelian characters

Question. Which of the folloiwng feature of RNA make it labile and easily degradable
(a) Single stranded nature
(b) 2′-OH group on sugar
(c) Phosphodiester bond
(d) Absence of Hydrogen bond

Question. What is the length and constituent base of tail in functional m-RNA
(a) Poly U – 200-300 bp
(b) Poly A – 200-300 bp
(c) Poly C – 200-300 nucleotides
(d) Poly A – 200-300 nucleotides

Question. DNA dependent RNA polymerases mediated synthesis of RNA over DNA called transcription.
About it which of the following statement is wrong
(a) In bacteria m-RNA doesnot required any processing to become active
(b) In eukaryotes there is clearcut division of labour in RNA polymerases
(c) Absence of introns in RNA of eukaryotes is reminiscent of antiquity
(d) RNA polymerase – III is responsible for synthesis of sn-RNA

Question. Which of the folloiwng cell cycle event is responsible for polyploidy phenomenon
(a) Failure of karyokinesis
(b) Failure of cytokinesis
(c) Failure of segregation
(d) Failure of non-disjunction

Question. Semiconservative replication of DNA in chromosomes was proved by
(a) Meselson & Stahl by using 15NH4Cl
(b) Taylor by using 15NH4Cl
(c) Meselson & Stahl by using tritiated thymidine
(d) Taylor by using tritiated thymidine

Question. Which of the following was not involved in deciphering of genetic code
(a) Physicist george Gamow’s permutation combination of 43 bases
(b) H.G. Khorana’s based synthesis of RNA molecules with defined combination of bases
(c) Severo ochoa enzyme for polymerising DNA with defined sequences
(d) Marshall Nirenberg’s cell free system for protein synthesis

Question. Which of the following mutation forms the genetic basis of proof that codon is a triplet and it is read in a continuous manner
(a) Chromosomal structural mutations
(b) Chromosomal numerical mutations
(c) Substitutional mutation
(d) Frame shift insertion or deletion mutation

Question. An adapter molecule that would on one hand read the code and on the other hand would bind to specific amino acids is
(a) m-RNA
(b) r-RNA
(c) t-RNA
(d) hm-RNA

Question. Which of the following r-RNA show structural as well as functional role in bacteria :-
(a) 16s rRNA
(b) 23s rRNA
(c) 5s rRNA
(d) 28s rRNA

Question. During transcription only one of the strand of DNA get transcribed. Which of the following reason explain it
(a) Otherwise one segment of DNA would be coding for two different proteins
(b) Otherwise dsRNA comes in existance
(c) Otherwise antisense RNA arise which donot participate in Translation
(d) All the above

Question. A transcription unit in DNA is defined primarily by three regions in DNA. These regions are
(a) Promoter, regulator and structural gene
(b) Promoter, structural gene and terminator
(c) Promoter, regulator and terminator
(d) Promoter, regulator and operator gene

Question. At which of the following levels, regulation of gene expression in eukaryotes donot occur
(a) Transcription level
(b) Processing level
(c) Transport of ribosomal subunits from nucleus to cytoplasm level
(d) Translation level

Question. Which of the following is not a goal of HGP
(a) Identify all the approximately 20,000-25,000 genes
(b) Store this information in database
(c) Restrict the related technologies so that other sector donot benefited with it
(d) Address the ethical, legal and social issues

Question. The human genome project was coordinated by
(a) U.S. department of energy
(b) National institute of health
(c) Sanger centre
(d) Both 1 and 2

Question. Which of the following organism was not used as model organism is human genome project
(a) Arabidopsis
(b) Caenorhabdities elegans
(c) Rice
(d) Hyacinthus orientalis

Question. Regarding to salient features of human genome select out the incorrect one
(a) Human genome contains 3164.7 million nucleotide bases
(b) Human genome contain 30,000 genes
(c) y-chromosome has largest number of genes
(d) 1.4 million locations are associated with SNPs

Question. If an inheritable mutation is observed in a population at high frequency, it is referred as
(a) DNA polyploidy
(b) DNA polymorphism
(c) DNA redundancy
(d) Sequence annotation

Question. Due to high degree of polymorphism, size of VNTR varies in size from
(a) 0.1 – 2 kb
(b) 0.1 – 2000 kb
(c) 0.1 – 20 kb
(d) 0.1 – 200 kb